ANAEROBE 2010 Congress Program

Wednesday July 7, 2010

0800-1700 Registration Opens
0900-1700 Anaerobe Identification & Susceptibility Workshop
Diane M. Citron, R.M. Alden Research Lab, Culver City, CA
Mike Cox, Anaerobe Systems, Morgan Hill, CA
Kerin L. Tyrrell, R.M. Alden Research Lab, Culver City, CA

Thursday July 8, 2010

0700 Registration / Continental Breakfast / Exhibits
0830-0840 Welcome
Bennett Lorber, M.D., President, Anaerobe Society
0840-0940 Keynote Address
Clinical Implications of Disturbances in the Human Microbiome
David Relman, M.D., VA Palo Alto Health Care System, Palo Alto, CA
0940-1030 Poster Session I / Exhibits
1030-1200 Colonic Microbiota: Luminal and Systemic Influence on Disease
Chair: C. Jeffrey Smith, Ph.D.
Probiotic Potential of a Commensal Bacterium in an Animal Model of Colitis
S. Melanie Lee, California Institute of Technology, Pasadena, CA
Microbial Translocation and Disease Progression in HIV and
Other Primate Lentiviral Infections

Jason M. Brenchley, Ph.D., Molecular Microbiology, NIAID, NIH, Bethesda, MD
Dominant "Indigenous" Bifidobacteria Isolated from Infant Faeces
Julio Aires, Ph.D. Universite Paris Descartes, France
Charcterizing Genomic Diversity of Fusobacterium nucleatum
from the Human Gut to Explain Differences in Virulence

Jaclyn Strauss, University of Guelph, Canada
1200-1330 Lunch / Exhibits / Student Competition Presentations
1330-1450 Vaginal Microbiota: The Complex Anaerobic Environment of Bacterial Vaginosis
Chair: Jeanne Marrazzo, M.D.
Use of Molecular Profiling to Describe the Spectrum and Dynamics of Vaginal Microbiota: An Update
David M. Fredricks, M.D., University of Washington, Seattle, WA
Easier to Grow than Identify: Characterization of "New" Bacteria from the Female Reproductive Tract
Sharon L. Hillier, Ph.D., University Pittsburgh, Pittsburgh, PA
Interpreting the Epidemiology and Natural History of Bacterial Vaginosis:
Are We Still Confused?

Jeanne Marrazzo, M.D., University of Washington, Seattle, WA
1450-1550 Poster Session II / Exhibits
1550-1730 Anaerobes in the Oral Cavity
Chair: Thomas E. Rams, D.D.S.
Bacterial Interference and Probiotics in Maintaining Health of the Oral Cavity
Jeffrey D. Hillman, D.M.D., Ph.D., Oragenics, Inc., Alachua, FL
The Oral Microbial "Canary in the Coal Mine" of Human Disease
Bruce Paster, Ph.D., Forsyth Dental Center, Boston, MA
Anaerobic Culture of Severe Early Childhood Caries
Anne Tanner, Ph.D., Forsyth Dental Center, Boston, MA
Periodontitis and Rheumatoid Arthritis: Two of a Kind?
Arie J. van Winkelhoff, Ph.D., University of Groningen, The Netherlands
Smoking Affects Subgingival Bacterial Acquisition and Colonization
Purnima Kumar, D.D.S., Ph.D., Ohio State University, Columbus, OH
1730-1800 Anaerobe Society Meeting
1800-1900 Wine & Cheese Reception

Friday July 9, 2010

0700 Registration / Continental Breakfast / Exhibits
0800-0930 Probiotics: Use and Mechanisms
Chair: Cynthia L. Sears, M.D.
The Use of Probiotics in Diarrheal Disease
Sherwood L. Gorbach, M.D., Tufts University School of Medicine, Boston, MA
Probiotics and Neonatal Necrotizing Enterocolitis
Erika C. Claud, M.D., University of Chicago, Chicago, IL
Mechanisms of Probiotic Action
James Versalovic, M.D., Ph.D., Baylor College of Medicine, Houston, TX
Molecular Characterisation of ABC-Type Multidrug Efflux Systems in
Bifidobacterium longum

Valerie R. Abratt, Ph.D., University of Cape Town, South Africa
0930-1030 Poster III / Exhibits
1030-1200 Diagnostic Methods & Microbiology
Chair: Roberta Carey, Ph.D.
Is Sequencing the Solution?
Brandi Limbago, Ph.D., Centers for Disease Control and Prevention, Atlanta, GA
Emerging Technologies to Identify Anaerobic Bacteria
Alida C. M. Wildeboer-Veloo, University Medical Center Groningen, The Netherlands
Tests to Detect Clostridium difficile: The Next Generation
Karen Carroll, M.D. The Johns Hopkins University, Baltimore, MD
Bacteroides Fragilis Fibrinogen Interactions
Sheila Patrick, Ph.D., DSc., Queens University Belfast, United Kingdom
Collagen Adhesins and Proteases of South African Clinical Strains of
Bacteroides Fragilis

Bruna Galvao, University of Cape Town, South Africa
1200-1315 Lunch / Exhibits
1315-1435 Clostridium difficile: Pathogenesis
Chair: David Aronoff, M.D.
Clostridium difficile-associated Disease: Considerations
Beyond the Gastrointestinal Tract

Jimmy D. Ballard, Ph.D., University of Oklahoma, Oklahoma City, OK
The Gastrointestinal Microbiota and Clostridium difficile
Vincent B. Young, M.D., Ph.D. University of Michigan, Ann Arbor, MI
The Role of the Toxins Tcda and Tcdb in Clostridium difficile Infection
Sarah A. Kuehne, Ph.D., University of Nottingham, United Kingdom
The Role of TcdC in the Virulence of Clostridium difficile
NAP1/027 Epidemic Strains

Glen P. Carter, Ph.D., Monash University, Australia
1435-1450 Break
1450-1600 Clostridium difficile: Epidemiology
Chair: Dale N. Gerding, M.D.
Controversies in Clostridium difficile Infection Epidemiology
L. Clifford McDonald, M.D., Centers for Disease Control and Prevention, Atlanta, GA
Trends of Clostridium difficile Infection in VA Hospitals and Proposed System Interventions
Stephen M. Kralovic, M.D., Cincinnati VA Medical Center, Cincinnati, OH
Contribution of a Government Target to Controlling Clostridium difficile in NHS
in England

Brian I. Duerden, M.D., Department of Health, United Kingdom
1600-1615 Break
1615-1730 Clostridium difficile: Treatment Options
Chair: Stuart Johnson, M.D.
Narrow Spectrum Antibiotics for Clostridium difficile Infection
Thomas J. Louie, M.D., University of Calgary, Canada
Intentional Colonization with Non-toxigenic Clostridium difficile to Manage
Recurrent Clostridium difficile Infection and Prevent Initial Clostridium difficile Infection

Dale N. Gerding, M.D., Loyola University, Chicago, IL
Antibodies to Clostridium difficile in Patients during Treatment with Metronidazole, Vancomycin or Tolevamer
Ian R. Poxton, Ph.D., University of Edinburgh, United Kingdom
Safety and Tolerability of an Oral Suspension of VP20621, Spores of a
Non-Toxigenic Clostridium difficile Strain; First in Human Administration
to Healthy Adult Subjects

Walter Tatarowicz, Ph.D., Viropharma, Exton, PA
1800 Buses to Congress Banquet - Mutter Museum

Saturday July 10, 2010

0730 Registration / Continental Breakfast / Exhibits
0830-0940 Veterinary Infections & Anaerobes in the Food Chain
Chair: J. Glenn Songer, Ph.D.
MLST and MLVA Analysis of Clostridium difficile Genotypes from
Food Animals, Foods, and Humans

Jane Marsh, Ph.D. University of Pittsburgh, Pittsburgh, PA
Pathogenesis of Enteric Infections by Clostridium perfringens type A
J. Glenn Songer, Ph.D., University of Arizona, Tucson, AZ
Identification of Novel Pathogenicity Loci-Associated with Avian Necrotic Enteritis-Producing Strains of Clostridium perfringens
Dion Lepp, University of Guelph, Canada
0940-1000 Break / Exhibits
1000-1145 An Update on Cytotoxic Clostridial Pathogens
Chair: Jimmy D. Ballard, Ph.D.
Toll-Like Receptors in the Innate Immune Response to Clostridium sordellii
Michael J. Aldape, Ph.D., Veterans Affairs Medical Center, Boise, ID
The Importance of Class A Scavenger Receptors in the Phagocytosis of
Clostridium sordellii

David Aronoff, M.D., University of Michigan, Ann Arbor, MI
Genetic Studies of Virulence Factors in Cytotoxic Clostridia
Dena Lyras, Ph.D., Monash University, Australia
Conjugative Plasmids in Clostridium botulinum
Eric Johnson, Ph.D., University of Wisconsin, Madison, WI
Requirements for the Germination of Clostridium sordellii Spores In vitro
Ernesto Abel-Santos, Ph.D., University of Nevada, Las Vegas, NV
Finding the Genes for Plasmalogen Biosynthesis in Clostridia
Howard Goldfine, Ph.D., University of Pennsylvania, Philadelphia, PA
1145-1315 Lunch / Exhibits
1315-1415 Anaerobes & Biotechnology: Opportunities for Microbiologists
Chair: Mike Cox
Anaerobes: History, Industry, and the Birth of Biotechnology
Mike Cox, Anaerobe Systems, Morgan Hill, CA
Anaerobes: A Piece in the Puzzle for Alternative Biofuels
Paul Lawson, Ph.D., University of Oklahoma, Norman, OK
1415-1430 Break
1430-1600 Antibiotics: Resistance & Susceptibility
Chair: David Hecht, M.D.
Current Trends in Antimicrobial Resistance among Anaerobes: Results from U.S. National Survey
David R. Snydman, M.D, Tufts Medical Center, Boston, MA
The European Experience on Antibiotic Resistance Patterns in Anaerobic
Bacteria: Clostridia & Bacteriods

Carl Erik Nord, M.D., Karolinska Institute, Sweden
Elisabeth Nagy, M.D., Ph.D., University of Szeged, Hungary
The FDA Approach to Antibiotics for the Treatment of Clostridium difficile-
Associated Disease.

Frederic J. Marsik, Ph.D., U.S. Food and Drug Administration
Resistance of Clostridium difficile to Cationic Antimicrobial Peptides
Shonna McBride, Tufts University School of Medicine, Boston, MA
1600-1615 Break
1615-1745 Clinical Aspects of Anaerobic Infections
Chair: Ellie J.C. Goldstein, M.D.
Antibiotic Development: Anything New for Anaerobes
Ellie J.C. Goldstein, M.D., University of California, Los Angeles, Santa Monica, CA
Fusobacterium necrophorum in Pharyngitis
Robert M. Centor, M.D., UAB Huntsville Regional Medical Campus, Huntsville, AL
Multi-Drug-Resistant Bacteroides fragilis Recovered from Blood and Severe Leg Wounds Caused by an IED in Afghanistan
Jeffrey Sherwood, M.D., Walter Reed Army Hospital, Washington, D.C.
The Dutch Approach to Antimicrobial Resistance Containment
John E. Degener, M.D., University Medical Centre Groningen, The Netherlands
Clostridium spp. in Stool Samples of Autistic Children
Gayane Martirosian, Ph.D, M.D., Medical University of Silesian, Poland
Antibacterial Activity of Tigecycline in Serum Against Anaerobes Associated with Diabetic Foot Infections
Gary E. Stein, Pharm.D., Michigan State University, Lansing, MI
1745-1800Closing Remarks

1 © 2010 Anaerobe Society of America